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What type of mutation has occurred in the following? Normal allele 5' - GGAAUGAAACAGGAACCC - 3' Mutant allele 5' - GGAAUGAAAUCAGGAACCC - 3'


A) Insertion of one base
B) Substitution
C) Deletion of one base
D) Insertion of two bases
E) Deletion of two bases

F) A) and C)
G) A) and E)

Correct Answer

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Which mutation in DNA would lead to the change of a single amino acid in a protein?


A) A nonsense mutation
B) A one base deletion
C) A one base insertion
D) A missense mutation
E) A frameshift

F) D) and E)
G) C) and E)

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In a "silent" mutation:


A) The codon that mutates causes a change in the amino acid specified
B) The codon that mutates does not cause a change in the amino acid specified
C) The codon that mutates causes a stop codon to occur instead of the placement of an amino acid
D) The mutation does not occur in a codon
E) The mutation is not in DNA

F) B) and E)
G) All of the above

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FOXP2 sequences were the most different between mice and _____.


A) Rhesus monkeys
B) Gorillas
C) Chimpanzees
D) Humans
E) All had the same number of changes from the mouse sequence

F) A) and B)
G) D) and E)

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If bacteria are infected with bacteriophage containing radioactive ____ the bacteria will now be radioactive.


A) Sulfur
B) Iron
C) Phosphate or sulfur
D) Iron or sulfur
E) Phosphate

F) C) and D)
G) A) and C)

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E

What would be the first codon translated in the mRNA sequence 5' - GGAAUGAAACAGGAACCC - 3'?


A) GGA
B) CCC
C) AUG
D) GAA
E) AAU

F) A) and E)
G) B) and D)

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How did the researchers estimate that the original mutation happened 3-400,000 years ago?


A) By examining the fossil record
B) Using a molecular clock
C) They found the mutation in chimpanzee DNA
D) They found the mutation in Neandertal DNA
E) They found the mutation in 300,000 year old human remains

F) A) and D)
G) D) and E)

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If the DNA in a cell consists of 20% A,it will be ___ T.


A) 30%
B) 80%
C) 40%
D) 20%
E) 10%

F) A) and B)
G) A) and C)

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D

The DNA sequence 5' - ATGCATGC - 3' will pair with which of the following RNA strands?


A) 5' - UAGCUAGC - 3'
B) 3' - UAGCUAGC - 5'
C) 3' - AUGCAUGC - 5'
D) 3' - TAGCTAGC - 5'
E) 5' - TAGCTAGC - 3'

F) B) and C)
G) B) and E)

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A somatic mutation is a mutation that occurs in cells that give rise to gametes.

A) True
B) False

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The strand of DNA that encodes the RNA molecule during transcription is the:


A) Lagging strand
B) Leading strand
C) Codon strand
D) Template strand
E) Parent strand

F) A) and B)
G) A) and C)

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A change in a cell's DNA sequence is:


A) Replication
B) Transcription
C) A mutation
D) Translation
E) An operon

F) D) and E)
G) C) and E)

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A proteome is all of the proteins an organism expresses throughout its life.

A) True
B) False

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An organism that receives recombinant DNA:


A) Has a genetic disease
B) Is a transgenic organism
C) Will develop cancer
D) Is sterile
E) Is a new species

F) C) and E)
G) B) and D)

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Based just on what is known about FOXP2,could Neandertals speak?


A) No, they have the same FOXP2 mutation as humans
B) Yes, they have the same FOXP2 mutation as humans
C) Yes, they have the same FOXP2 sequence as chimpanzees
D) No, they have the same FOXP2 sequence as chimpanzees
E) Yes, they have the same FOXP2 sequence as both humans and chimpanzees

F) A) and E)
G) None of the above

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In eukaryotes an mRNA molecule can only be translated by one ribosome at a time.

A) True
B) False

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How did the researchers initially estimate that the original mutation happened 200,000 years ago?


A) They found the mutation in Neandertal DNA
B) By examining the fossil record
C) They found the mutation in chimpanzee DNA
D) Using a molecular clock
E) They found the mutation in 300,000-year-old human remains

F) B) and E)
G) B) and C)

Correct Answer

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An antisense RNA is complementary to a mRNA and could:


A) Prevent transcription of the mRNA
B) Increase translation of the mRNA
C) Increase transcription of the mRNA
D) Prevent translation of the mRNA
E) Mutate the mRNA sequence

F) B) and E)
G) All of the above

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D

Amanatin is a toxin found in the death cap mushroom,Amanita phalloides.It inhibits RNA polymerase,thus blocking:


A) Transcription
B) Translation
C) Replication
D) Cell division
E) RNA splicing

F) C) and E)
G) None of the above

Correct Answer

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There are only two main types of RNA needed to make proteins.They are tRNA and rRNA.

A) True
B) False

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