Question 1

The biodegradation pathway for benzoate is likely to be subject to induction rather than repression.

Accepted Answer

A) True 
 B)False

Question 2

The actual residues in a DNA-binding protein that interacts with DNA usually correspond to each other according to the amino acids encoded by the DNA.For example,a DNA sequencing containing AGC-AGA-CAG which encodes for Ser-Arg-Gln would likely have a DNA-binding protein with Ser-Arg-Gln bind to it.

Accepted Answer

A) True 
 B)False  False

Question 3

Cyclic AMP (cAMP)is involved in the global regulation of catabolic pathways in Escherichia coli,including the lac operon,and a low activity of adenylate cyclase that makes cAMP is suggestive of catabolite repression.

Accepted Answer

A) True 
 B)False

Question 4

How is transcription in Archaea controlled?

Accepted Answer

Archaea have mechanisms to control trans...

Question 5

Describe the function and the functional components of the maltose regulon system.

Accepted Answer

The textbook shows each component of the...

Question 6

Regulation of an enzyme's activity occurs

Accepted Answer

A)   transcriptionally.
B)   translationally.
C)   posttranslationally.
D)   at any point on the enzymatic production pathway.E) A) and C)
F) A) and B) C

Question 7

Explain the function of cAMP in catabolite repression.

Accepted Answer

Adenylate cyclase synthesizes the regula...

Question 8

Transcriptomics is a common approach to infer which metabolic pathways are actively functioning,but which regulation process can MOST significantly complicate or even abolish conclusions from this approach?

Accepted Answer

A)   activity of a catabolite repressor protein on multiple pathways
B)   antisense RNA silencing
C)   feedback inhibition with allosteric proteins
D)   presence of corepressors and inducers which are molecules undetected by transcriptomicsE) All of the above
F) C) and D)

Question 9

Based on our understanding of the early stages of life,________ is/are thought to be one of the earliest forms of metabolic regulation that evolved.

Accepted Answer

A)   attenuation
B)   feedback inhibition
C)   riboswitches
D)   transcription factorsE) A) and D)
F) C) and D)

Question 10

Post-translational regulation of an enzyme's activity,such as glutamine synthetase,can be finely controlled at varied levels due to

Accepted Answer

A)   the varied strengths metabolite-regulating compounds can have with the enzyme such as hydrogen bonding, covalent bonding, and van der Waals attractions.
B)   having multiple independently functional subunits.
C)   the structural strength enzymes have once properly folded compared to short-lived and easily degradable transcripts during translational regulation.
D)   weak chemical modifications of the enzyme rather than harsh protein-protein or protein-DNA interactions.E) A) and C)
F) All of the above

Question 11

A common structure for proteins that bind DNA is helix-turn-helix.

Accepted Answer

A) True 
 B)False

Question 12

Quorum sensing requires a strong gradient to be reached before the signaling molecules are transported into the cytoplasm.

Accepted Answer

A) True 
 B)False

Question 13

Multiple sigma factors are essential to induce the biosynthesis of endospores,all of which are encoded by genes,so a complex regulatory mechanism such as this likely has a higher chance of mutations leading to incorrect functioning compared to a simple repression mechanism.

Accepted Answer

A) True 
 B)False

Question 14

How could you identify potential riboswitches with bioinformatics tools?

Accepted Answer

A)   Advanced 3D modeling techniques of mRNA folding would be necessary because complementary nucleotide binding predictions would not be useful.
B)   Locate short regions of an individual transcript with several complementary sites.
C)   Identify homologous sRNAs in other organisms.
D)   Identify several complementary mRNAs encoded in the genome.E) B) and D)
F) A) and D)

Question 15

Explain the sequence of events that would follow the transfer of an organism from a complex medium to a minimal medium.

Accepted Answer

Answers will vary but should include the...

Question 16

Which type of regulator(s) specifically bind to operator regions of DNA?

Accepted Answer

A)   activators
B)   activators and inducers
C)   repressors
D)   repressors and corepressorsE) B) and C)
F) A) and D)

Question 17

In catabolic repression,cells use the least abundant carbon source first.

Accepted Answer

A) True 
 B)False

Question 18

Once the regulatory proteins and effector molecules are made,the actual mechanisms for regulation rarely require net energy input.

Accepted Answer

A) True 
 B)False

Question 19

Transcriptional regulators bind most frequently at the ________ site of DNA.

Accepted Answer

A)   major groove
B)   minor groove
C)   histone complex
D)   primary supercoilE) C) and D)
F) A) and B)

Question 20

During a growth curve of Aliivibrio fischeri,when would you expect to see the strongest bioluminescence?

Accepted Answer

A)   lag phase
B)   early to middle log phase
C)   late log to early stationary phase
D)   middle to late stationary phaseE) None of the above
F) A) and B) C

Exam 7: Metabolic Regulation

The biodegradation pathway for benzoate is likely to be subject to induction rather than repression.

Correct AnswerverifiedShow Answer

Correct AnswerverifiedFalse

Cyclic AMP (cAMP)is involved in the global regulation of catabolic pathways in Escherichia coli,including the lac operon,and a low activity of adenylate cyclase that makes cAMP is suggestive of catabolite repression.

Correct AnswerverifiedShow Answer

How is transcription in Archaea controlled?

Correct AnswerverifiedArchaea have mechanisms to control trans...View AnswerShow Answer

Describe the function and the functional components of the maltose regulon system.

Correct AnswerverifiedThe textbook shows each component of the...View AnswerShow Answer

Regulation of an enzyme's activity occurs

Correct AnswerverifiedC

Explain the function of cAMP in catabolite repression.

Correct AnswerverifiedAdenylate cyclase synthesizes the regula...View AnswerShow Answer

Transcriptomics is a common approach to infer which metabolic pathways are actively functioning,but which regulation process can MOST significantly complicate or even abolish conclusions from this approach?

Correct AnswerverifiedShow Answer

Based on our understanding of the early stages of life,________ is/are thought to be one of the earliest forms of metabolic regulation that evolved.

Correct AnswerverifiedShow Answer

Post-translational regulation of an enzyme's activity,such as glutamine synthetase,can be finely controlled at varied levels due to

Correct AnswerverifiedShow Answer

A common structure for proteins that bind DNA is helix-turn-helix.

Correct AnswerverifiedShow Answer

Quorum sensing requires a strong gradient to be reached before the signaling molecules are transported into the cytoplasm.

Correct AnswerverifiedShow Answer

Multiple sigma factors are essential to induce the biosynthesis of endospores,all of which are encoded by genes,so a complex regulatory mechanism such as this likely has a higher chance of mutations leading to incorrect functioning compared to a simple repression mechanism.

Correct AnswerverifiedShow Answer

How could you identify potential riboswitches with bioinformatics tools?

Correct AnswerverifiedShow Answer

Explain the sequence of events that would follow the transfer of an organism from a complex medium to a minimal medium.

Correct AnswerverifiedAnswers will vary but should include the...View AnswerShow Answer

Which type of regulator(s) specifically bind to operator regions of DNA?

Correct AnswerverifiedShow Answer

In catabolic repression,cells use the least abundant carbon source first.

Correct AnswerverifiedShow Answer

Once the regulatory proteins and effector molecules are made,the actual mechanisms for regulation rarely require net energy input.

Correct AnswerverifiedShow Answer

Transcriptional regulators bind most frequently at the ________ site of DNA.

Correct AnswerverifiedShow Answer

During a growth curve of Aliivibrio fischeri,when would you expect to see the strongest bioluminescence?

Correct AnswerverifiedC

Correct Answer
verified

Correct Answer
verified
False

Correct Answer
verified

Correct Answer
verified
Archaea have mechanisms to control trans...
View Answer

Correct Answer
verified
The textbook shows each component of the...
View Answer

Correct Answer
verified
C

Correct Answer
verified
Adenylate cyclase synthesizes the regula...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Answers will vary but should include the...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
C