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The causative agent of Lyme disease is ______.


A) Borrelia burgdorferi
B) Borrelia hermsii
C) Ixodes pacificus
D) Ixodes scapularis
E) Leptospira interrogans

F) B) and E)
G) D) and E)

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The heart wall has three layers. In order from the outer layer to the inner layer, they are ______.


A) endocardium, myocardium, and epicardium
B) myocardium, endocardium, and epicardium
C) endocardium, epicardium, and myocardium
D) epicardium, myocardium, and endocardium

E) A) and C)
F) B) and C)

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Humans should be routinely vaccinated against Lyme disease.

A) True
B) False

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Rifampin is the drug of choice for malaria.

A) True
B) False

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The cyclic bouts of fever and chills in malaria are caused by _______.


A) white blood cell lysis
B) neurological involvement
C) red blood cell lysis
D) the timing of the viral life cycle

E) B) and C)
F) A) and C)

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The causative agent in a case of sepsis can be isolated by _______.


A) inoculating blood agar with a sample of the patient's blood
B) sending a blood sample to the CDC laboratories in Atlanta
C) performing a Kirby-Bauer assay on a sample of the patient's blood
D) centrifugation of the blood to separate cells and plasma

E) C) and D)
F) None of the above

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The presence of viruses in the blood is called ______.


A) viremia
B) hemovirus
C) fungemia
D) septicemia

E) None of the above
F) A) and D)

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Control of rodent populations is important for preventing ______.


A) brucellosis
B) plague
C) Q fever
D) malaria

E) A) and B)
F) All of the above

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Ehrlichiosis, Rocky Mountain Spotted Fever, dengue fever, and tularemia are all infectious diseases of the cardiovascular system. What feature do they have in common?


A) The causative agent of each of these diseases is a bacterium.
B) They are all endemic in the mountain states in the western United States.
C) People with immune deficiencies are especially susceptible to these diseases.
D) They are all transmitted by arthropod vectors.

E) B) and D)
F) B) and C)

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You just returned from a hiking/camping trip and are experiencing symptoms of an infection: high fever, swollen lymph nodes, and black-and-blue marks or hemorrhages under the skin. Your doctor asks if you have been in the four corners area of the United States (where the states of Arizona, colorado, New Mexico, and Utah all meet) . What does the doctor suspect?


A) You might have picked up the plague bacterium from ?eas that normally feed on rodents in that area.
B) Those four states have high rates of Chikungunya, which is what the doctor suspects that you have.
C) Hemorrhagic fever is often associated with bats in that region of the United States.
D) Since there are many mosquitoes in that area, you might have been infected with Plasmodium.

E) A) and C)
F) None of the above

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Most cases of sepsis are caused by ______.


A) viruses
B) bacteria
C) prions
D) protozoans
E) fungi

F) B) and C)
G) None of the above

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In severe cases of Rocky Mountain spotted fever, the enlarged lesions of the rash can become necrotic and predispose the patient to gangrene of toes and ?ngertips.

A) True
B) False

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Anthrax is ______.


A) a zoonosis
B) transmitted by contact, inhalation, or ingestion
C) a disease that, in humans, can cause a rapidly fatal toxemia and septicemia
D) only seen sporadically in the United States
E) All of the choices are correct.

F) A) and E)
G) A) and D)

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Which of the following statements regarding the structure of blood vessels is incorrect?


A) Blood vessels are often found in parallel with lymphatic vessels.
B) Capillaries have only a single layer of endothelium, rendering them fragile and leaky during an infection with a hemorrhagic fever virus.
C) Connective tissue and muscle fibers are found in the layers of tissue surrounding both arteries and veins.
D) In contrast to veins, arteries have higher blood pressure, more tissue layers, and are thinner vessels.

E) A) and B)
F) A) and C)

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Which drug interferes with the action of an HIV enzyme needed for final assembly and maturation of the virus?


A) Fusion inhibitor
B) Integrase inhibitor
C) Reverse transcriptase inhibitor
D) Protease inhibitor

E) A) and C)
F) A) and B)

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Your patient was admitted for a gunshot wound about a week ago. As a precautionary activity, the doctor placed her on antibiotics for a few days while recuperating. Blood specimens are drawn on the patient a several times daily and sent to the microbiology lab for analysis of bacteria. Nothing Has grown in culture. On her 4th day in the hospital, she has had no fever and no other signs of infection, but one set of blood specimens has been reported positive for a bacterium. The culture was identi?ed by the lab as Staphylococcus epidermidis, a common organism on the skin. Predict the likely situation leading to this.


A) Staphylococcus epidermidis is a very slow growing bacterium and was probably in the blood right after the gunshot wound, but failed to grow until now.
B) The patient is immunodepressed and very susceptible to bacterial infection.
C) Staphylococcus epidermidis is a skin contaminant that ended up in the blood specimen as a consequence of poor aseptic technique during the venipuncture.
D) Staphylococcus epidermidis has converted to a pathogen because of the antibiotics prescribed for the patient.

E) C) and D)
F) None of the above

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Malaria may be prevented by ________.


A) using bed nets sprayed with insecticide
B) eliminating standing water
C) taking prophylactic drugs
D) using genetically engineered mosquitoes
E) All of the choices are correct.

F) A) and E)
G) A) and D)

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Lyme disease involves ______.


A) early symptoms of fever, headache, and stiff neck
B) crippling polyarthritis, cardiovascular issues, and neurological problems
C) people exposed to wooded or forested areas
D) treatment with antimicrobials
E) All of the choices are correct.

F) A) and D)
G) A) and E)

Correct Answer

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Symptoms of infectious mononucleosis include _______.


A) fever and pocks on skin
B) fever, severe diarrhea, pneumonitis, hepatitis, and retinitis
C) vesicular lesions in oral mucosa
D) sore throat, fever, cervical lymphadenopathy, and splenomegaly

E) A) and B)
F) None of the above

Correct Answer

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A common cardiovascular/lymphatic system disease in AIDS patients is ______.


A) Burkitt's lymphoma
B) cytomegalovirus
C) acute endocarditis
D) brucellosis
E) ehrlichiosis

F) D) and E)
G) B) and D)

Correct Answer

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